Roger Black has interviewed David Berlow on an alternative solution (sorry, contention) of on-screen antialiasing. Berlow proposes abandoning the conventional multiple master approach in favour of creating multiple versions of the same vector typeface, hand-optimised to specific type sizes designed on the pixel grid itself. More importantly he notes that the nature of the argument, ie, that one method is best, is to miss the point, and the graphic designer (and indeed the viewer) should be free to pick the method (Berlow's or otherwise) that is best for the design and particular viewing conditions themselves. It is interesting reading. Oh, and Roger, your website is darn pretty, but I'm not sure it needs to be 4 foot wide...
Source: type4screen